Sjogren's syndrome treated with bromhexine: a reassessment.
نویسندگان
چکیده
منابع مشابه
Sjörgren's syndrome treated with bromhexine: a randomised clinical study.
Existing treatment for Sjögren's syndrome is unsatisfactory, and uncontrolled observations have suggested that bromhexine may be effective. Twenty-nine patients with Sjögren's syndrome were therefore assigned to two randomised double-blind crossover trials with bromhexine and placebo, each comprising two two-week periods. In the first trial bromhexine 24 mg/day was given by mouth; in the second...
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The ‘classical’ model to explain glandular hypofunction in Sjögrens syndrome (SS) is tissue loss secondary to immune attack mediated by a combination of apoptosis and cytotoxic cell death (reviewed recently by Ramos-Casals and Font [1]). In this model, the process of glandular destruction is made self-sustaining by the continued production of novel ‘self ’ antigens, secondary to apoptotic bleb ...
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Background Sjogrens syndrome (SS) is a chronic autoimmune disorder, characterised by lymphocytic infiltration resulting in exocrine gland destruction and other extra-glandular manifestations [1]. Currently there is no definitive diagnostic test, and the immuno-pathology is not fully understood. Recently focus has shifted to investigating microRNAs (miRs) in an effort to understand the mechanism...
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ژورنال
عنوان ژورنال: BMJ
سال: 1980
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.281.6249.1216-a